Cerebral Blood Flow Velocity and Arterial Pressure Model - Based Noninvasive Estimation of Intracranial Pressure from

نویسنده

  • Faisal M. Kashif
چکیده

measurement. real-time estimation of ICP could spare patients the pain of and recovery from more invasive methods of immediately upon examining a patient. Such a model-based approach will find use in many clinical situations where it does not require calibration or training before application. This feature makes it amenable to use in the clinic, is that −− other than its ability to estimate ICP noninvasively −− et al. The beauty of the model described by Kashif waveforms, correctly identifying elevated ICP (>20 mmHg) with high sensitivity and specificity. authors' model to estimate ICP. These estimated values were compared to the patient's actual invasive ICP (taken from the radial artery) and CBF velocity (from transcranial ultrasound), which were then plugged into the and brain tissue as the capacitor. Hospital records of 37 patients with traumatic brain injury contained data for ABP as the respective voltage and current, the cerebral vasculature as the resistor, and the compliance of the vasculature (CBF), and ICP. Using an electrical circuit as an analog, Kashif and colleagues were able to describe ABP and CBF cerebrospinal fluid. The variables involved in this model included arterial blood pressure (ABP), cerebral blood flow The authors created a simplified model of what's inside our heads: brain tissue, blood vessels, and estimating the pressure using tools already available in the clinic. have developed a noninvasive method of et al. ICP monitoring available to a larger patient population, Kashif are avoided in routine assessment of other neuropathologies that could benefit from knowing this vital sign. To make is important for patients with severe neurological trauma, but because the process is so invasive, ICP measurements inserted through a hole in the skull, directly into the brain or surrounding space. Monitoring intracranial pressure (ICP) Measuring the pressure inside your head is no trivial task. It currently requires an invasive probe or catheter, Under Pressure

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Award Number: W81XWH-11-1-0676 TITLE: Model-Based, Noninvasive Monitoring of Intracranial Pressure PRINCIPAL INVESTIGATOR:

• I Hwang, FM Kashif, GC Verghese, T Heldt. A frequency-domain approach to model-based noninvasive intracranial pressure estimation from arterial blood pressure and cerebral blood flow velocity. Invited contribution to the Minisymposium on Information Derived from the Arterial Blood Pressure Waveform and Its Significance. IEEE Engineering in Medicine and Biology Conference, San Diego, CA, Septe...

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Model-based noninvasive estimation of intracranial pressure from cerebral blood flow velocity and arterial pressure.

Intracranial pressure (ICP) is affected in many neurological conditions. Clinical measurement of pressure on the brain currently requires placing a probe in the cerebrospinal fluid compartment, the brain tissue, or other intracranial space. This invasiveness limits the measurement to critically ill patients. Because ICP is also clinically important in conditions ranging from brain tumors and hy...

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Kashif Cerebral Blood Flow Velocity and Arterial Pressure Model - Based Noninvasive Estimation of Intracranial Pressure from

measurement. real-time estimation of ICP could spare patients the pain of and recovery from more invasive methods of immediately upon examining a patient. Such a model-based approach will find use in many clinical situations where it does not require calibration or training before application. This feature makes it amenable to use in the clinic, is that −− other than its ability to estimate ICP...

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تاریخ انتشار 2012